Claude of Lorraine, duke of Guise Duke of Guise (1496–1550) Parents Philippa of Guelders René II of Lorraine Children Louise of Lorraine François de Guise Louis I of Lorraine, cardinal of Guise Claude of Lorraine, duke of Aumale Charles, Cardinal of Lorraine Mary of Lorraine Francis, Duke of Guise Renee de Guise Pierre de Guise Antonie de Guise René of Lorraine, marquis of Elbeuf Philippe de Guise Siblings Antoine, Duke of Lorraine François de Lorraine Jean, Cardinal of Lorraine Louis, Count of Vaudémont Charles de Lorraine Isabelle de Lorraine Anne de Lorraine Nicholas de Lorraine Catherine de Lorraine François de Lorraine Claude de Lorraine Partners Antoinette de Bourbon
