Isabella Borgia Roman lady, daughter of future pope Alexander VI (1471 - 1541) (1471–1541) Parents Alexander VI unknown woman Children Giulia Matuzzi Siblings Girolama Borgia Gioffre Borgia Lucrezia Borgia Gioffre Borgia Giovanni Borgia, 2nd Duke of Gandia Pier Luigi de Borgia Giovanni Borgia Laura Orsini Rodrigo Borgia Cesare Borgia Partners Pietro Matuzzi